By Tzvi Tzfira,Vitaly Citovsky
Agrobacterium is a plant pathogen which factors the “crown-gall” affliction, a neoplastic progress that effects from the move of a well-defined DNA phase (“transferred DNA”, or “T-DNA”) from the bacterial Ti (tumor-inducing) plasmid to the host telephone, its integration into the host genome, and the expression of oncogenes contained at the T-DNA. The molecular equipment, wanted for T-DNA iteration and delivery into the host mobile and encoded through a sequence of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the topic of various experiences during the last numerous many years. at the present time, Agrobacterium is the software of selection for plant genetic engineering with an ever increasing host variety that comes with many commercially vital plants, vegetation, and tree species. additionally, its fresh program for the genetic transformation of non-plant species, from yeast to cultivated mushrooms or even to human cells, can provide this bacterium a distinct position sooner or later of biotechnological functions.
The publication is a complete quantity describing Agrobacterium's biology, interactions with host species, and makes use of for genetic engineering.
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Agrobacterium: From Biology to Biotechnology by Tzvi Tzfira,Vitaly Citovsky